ABSTRACT
Algunos microorganismos como Chlamydia trachomatis, Ureaplasma urealyticum y Mycoplasma hominis han sido relacionados con diferentes procesos patológicos en mujeres sexualmente activas. OBJETIVO: Para conocer la frecuencia de estos agentes se realizó un estudio descriptivo observacional en el Hospital Ginecoobstétrico Ramón González Coro, en el período de noviembre de 2008 a enero de 2009. MÉTODOS: Se estudiaron 166 muestras de exudados vaginales y endocervicales tomadas a pacientes que acudieron a las consulta de infertilidad y abortadoras habituales. Se aplicaron los test diagnósticos para Chlamydia y micoplasmas genitales. RESULTADOS: De las pacientes estudiadas, 113 fueron positivas (68 por ciento), el test de Chlamydia se aplicó y 75 resultaron positivas a este microorganismo (45,2 por ciento), mientras que 57 fueron positivas a micoplasmas genitales (34,3 por ciento), de ellas 50 a Ureaplasma urealyticum, 4 a Mycoplasma hominis y en 3 muestras se aislaron Ureaplasma urealyticum más Mycoplasma hominis. Se encontró asociación de estos agentes con otros microorganismos. El 50,9 por ciento de los casos positivos a Mycoplasma tuvieron una infección moderada (29/57). El test de Mycoplasma permitió conocer la susceptibilidad de estos agentes frente a diferentes antimicrobianos; se encontró para Ureaplasma urealyticum una resistencia de 24 por ciento para la ofloxacina; 22 por ciento para la tetraciclina y 20 por ciento para la claritromicina; por su parte Mycoplasma hominis mostró el 75 por ciento de resistencia a la eritromicina y 100 por ciento a claritromicina y azitromicina; en los tres casos que coincidieron Ureaplasma urealyticum y Mycoplasma hominis se observó una resistencia elevada a la azitromicina, eritromicina y claritromicina. Hubo una alta sensibilidad frente minociclina y clindamicina. CONCLUSIONES: El microorganismo más frecuente en este estudio resultó C. trachomatis, M. hominis reportó más resistencia a los antimicrobianos que U. ure...
Some microorganisms like the Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma homonis have been related to different pathological processes in women sexually actives. OBJECTIVE: To know the frequency of these agents a observational and descriptive study was conducted in the "Ram¾n Gonzßlez Coro" Gynecology and Obstetrics Hospital from November, 2008 to January, 2009. METHODS: One hundred and sixty six samples of vaginal exudates from patients seen in infertility consulting rooms with regular abortions were studied. Diagnostic tests for Chlamydia and genital Mycoplasm tests were applied. RESULTS: From the study patients, 113 were positive (68 percent), Chlamydia test was applied and 75 were positive to this microorganism (45.2 percent), whereas 57 were positive to genital micoplasma (34.3 percent), from them 50 were positive to Uraplasma urealyticum, 4 to Mycoplasma homonis, and in three samples Ureaplasma urealyticum and Mycoplasma homonis were isolated. There was association of these agents with other microorganisms. The 50.9 percent of cases positive to Mycoplasma had a moderate infection (29/57). The Mycoplasma's test allowed to know the susceptibility of these agents to different antimicrobial agents, in the case of Ureaplasma urealyticum there was a resistance of 24 percent to Ofloxacin; 22 percent to Tetracycline, and the 20 percent to Clarithromycin; Mycoplasma hominis showed a 75 percent of resistance to erythromycin and the 100 percent to Claritromycin and to Azithromycin in the thre cases where they coindiced. Ureaplasma urealyticum and Mycoplasma hominis had a significant resistance to Azithromycin, Eritromycin and Claritromycin. There was a high level of sensitivity to minocycline and to clindamycin. CONCLUSIONS: The more frequent microorganism in present study was the C. trachomatis, and M. hominis had more resistance to antimicrobials agents than U.uralyticum, both are very sensitive to minocycline and ...